MTBE (methyl tert-butyl ether)

CAS

Purity

CHARACTER

methyl tert-butyl ether (MTBE), chemical formula C5H12O, is a colorless transparent liquid, insoluble in water but soluble in ethanol. MTBE is an excellent high-octane gasoline additive and antiknock agent, which can significantly improve the combustion efficiency and power performance of gasoline and reduce harmful substances emissions. It is also widely used in the chemical industry to produce high-purity isobutylene by cracking for the production of butyl rubber, methyl methacrylate and other chemical products. In addition, MTBE is also used in medicine, water treatment and other fields, such as as drug excipients and extractants. As a multifunctional organic compound, methyl tert-butyl ether plays an important role in many fields such as energy, chemical industry and environmental protection.

APPLICATIONS

(1) The main use of methyl tert-butyl ether (MTBE) is as a raw material for the production of finished gasoline, accounting for more than 90% of the total demand for methyl tert-butyl ether. It can increase the octane number of gasoline, enhance the anti-knock resistance of gasoline, improve the combustion performance of gasoline, make gasoline burn more thoroughly, and reduce carbon monoxide emissions.

(2) Methyl tert-butyl ether can be cracked to generate high-purity isobutylene, which is used in the field of fine chemicals. The main products include butyl rubber, polyisobutylene, methyl methacrylate and other organic chemical products. For example, butyl rubber is a kind of synthetic rubber made by copolymerization of isobutylene and a small amount of isoprene at low temperature. It has good air tightness, water tightness, chemical stability and thermal stability. It is widely used in tire inner tubes, water tires, vulcanized capsules, wires and cables, waterproof building materials, shock-absorbing materials and other products.

(3) Methyl tert-butyl ether is also used in the field of medicine. It is often used as a pharmaceutical intermediate for the manufacture of drugs and preparations, such as acetaminophen and some sedatives. However, as a pharmaceutical intermediate, the purity and character stability of methyl tert-butyl ether are required to be higher, and the corresponding added value and price of the product are also higher.

(4) Methyl tert-butyl ether can also be used as a solvent and reaction medium, as a medium and catalyst in chemical reactions, and for separating and processing compounds, preparing samples and measuring material properties in scientific laboratories.

(5) Methyl tert-butyl ether has a unique ether taste and relatively stable properties, so it is also widely used in the processing of edible flavors. It can be used in foods such as flavoring agents, sweeteners, chewing gum, mints and mouth-dissolving tablets to improve their taste and smell; it can also be used in beverages, beer, wine and fruit drinks to improve their freshness and taste.

ABILITIES

1. Packing: barreled, scattered water
2. Logistics: car transportation, shipping
3. Payment request: EXW/FOB/FCA/CFR only accepted

HONORARY

Chinese name	methyl tert-butyl ether
English Name	tert-Butyl methyl ether
Alias	MTBE Methyl tert-butyl ether Methyl tert-butyl ether tert-butyl methyl ether 2-methoxy-methylpropane tert-butyl methyl ether MTBE 2-methyl-2-methoxypropane Methyl tert-butyl ether (MTBE) 2-methoxy-2-methylpropane
English alias	MTBE Methyl-tert-bu tert-Butyl methyl ether Methyl tert-butyl ether, for residue analysis
CAS	1634-04-4
EINECS	216-653-1
Chemical formula	C5H12O
molecular weight	88.15
InChIKey	BZLVMXJERCGZMT-UHFFFAOYSA-N
Density	0.7404
Melting Point	-110°C
Boiling Point	55-56°C(lit.)
Flash Point	-27 °F
water soluble	51 g/L (20 °C)
Vapor pressure	4.05 psi ( 20 °C)
steam density	3.1 (vs air)
Solubility	42g/l
refractive index	n20/D 1.369(lit.)
Storage conditions	Store at +2°C to +25°C.
Stability	Stable, but may form explosive peroxides in contact with air. Extremely flammable-note low flash point. Incompatible with strong oxidants.
Appearance	Powder or needle
Specific Gravity	0.740
Color	APHA: ≤10
Smell	Characteristic ethereal odor
Maximum wavelength (λmax)	['λ: 210 nm Amax: 1.0', , 'λ: 225 nm Amax: 0.50', , 'λ: 250 nm Amax: 0.10', , 'λ: 300
Merck	14,6032
BRN	1730942
Explosion limit value	1.5-8.5%(V)
Exposure Limits	ACGIH: TWA 50 ppm
physicochemical properties	Colorless, low viscosity liquid with terpene-like odor. Slightly soluble in water, but miscible with many organic solvents.
Dangerous Goods Signs	Xn-Hazardous Materials F-Flammable Materials Xi-Irritant Materials T-Toxic Materials
Risk Terms	R36/37/38-Irritating to eyes, respiratory system and skin. R40-A few reported carcinogenic consequences. R38-Irritated skin. R11-highly flammable. R39/23/24/25 - R23/24/25-Toxic by inhalation, skin contact and swallowing.
Safety terminology	S9-Keep the container in a well-ventilated place. S16-Keep away from sources of ignition. S24-Avoid skin contact. S45-In the event of an accident or feeling unwell, seek medical attention immediately (if possible, show their label). S36/37-Wear appropriate protective clothing and gloves. S7-Keep container sealed.
Dangerous Goods Transport No.	UN 2398 3/PG 2
WGK Germany	3
RTECS	KN5250000
FLUKA BRAND F CODES	3-10
TSCA	Yes
Customs Number	2909 19 90
Hazard Class	3
Packing Group	II
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Methyl tert-Butyl Ether- Introduction

Methyl tert-butyl ether (MTBE) is a common organic compound with the chemical formula C5H12O. The following is an introduction to the properties, uses, preparation methods and safety information of methyl tert-butyl ether:

properties:
-appearance: colorless liquid
-solubility: soluble in water, alcohol and ether solvents
-melting point:-110 c
-boiling point: 55-56 c (lit.)
-density: 0.7404

uses:
-neutral solvent: methyl tert-butyl ether is often used as a neutral solvent in the chemical industry, it can dissolve many organic substances.
-Gasoline additive: Methyl tertiary butyl ether is added to gasoline, which can improve combustion efficiency and anti-knock resistance, help reduce exhaust emissions, and improve the impact resistance of gasoline.
-Chemical intermediate: MTBE is also an intermediate product of many chemical reactions and can be used to synthesize other organic compounds.

preparation method: The common preparation method of
methyl tert-butyl ether is obtained by reacting isobutylene with methanol. The reaction equation is as follows:
C4H8 CH3OH → C5H12O

safety information:
-methyl tert-butyl ether is flammable, avoid contact with open flames or high temperature substances, and store in a cool and ventilated place.
-Avoid inhaling methyl tert-butyl ether vapors and avoid contact with skin and eyes.
-Methyl tert-butyl ether may have a negative impact on the environment, so the relevant regulations on environmental protection should be observed when using and handling.
-In industrial processes, appropriate safety measures should be taken, including the wearing of personal protective equipment such as protective glasses, respirators and protective gloves.

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Chemical Safety Data Sheet MSDS / SDS

tert-Butyl methyl ether

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: tert-Butyl methyl ether
CBnumber: CB2853178
CAS: 1634-04-4
EINECS Number: 216-653-1
Synonyms: MTBE,TBME

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P501 Dispose of contents/container to..…

P405 Store locked up.

P403+P235 Store in a well-ventilated place. Keep cool.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P370+P378 In case of fire: Use … for extinction.

P308+P313 IF exposed or concerned: Get medical advice/attention.

P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P271 Use only outdoors or in a well-ventilated area.

P264 Wash skin thouroughly after handling.

P264 Wash hands thoroughly after handling.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.

P240 Ground/bond container and receiving equipment.

P233 Keep container tightly closed.

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P202 Do not handle until all safety precautions have been read and understood.

P201 Obtain special instructions before use.

Hazard statements

H335 May cause respiratory irritation

H336 May cause drowsiness or dizziness

H351 Suspected of causing cancer

H319 Causes serious eye irritation

H315 Causes skin irritation

H304 May be fatal if swallowed and enters airways

H303 May be harmfulif swallowed

H225 Highly Flammable liquid and vapour

SECTION 3: Composition/information on ingredients

Substance

Product name: tert-Butyl methyl ether
Synonyms: MTBE,TBME
CAS: 1634-04-4
EC number: 216-653-1
MF: C5H12O
MW: 88.15

SECTION 4: First aid measures

Description of first aid measures

General advice

Show this material safety data sheet to the doctor in attendance.

If inhaled

After inhalation: fresh air.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed

After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free. Pulmonary failure possible after aspiration of vomit. Call a physician immediately.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media

Carbon dioxide (CO2) Foam Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides Combustible.

Pay attention to flashback.

Vapors are heavier than air and may spread along floors.

Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.

Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.

Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.

Environmental precautions

Do not let product enter drains. Risk of explosion.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb? ). Dispose of properly. Clean up affected area.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Advice on protection against fire and explosion

Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.

Hygiene measures

Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits

Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other

substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,4 mm Break through time: 120 min

Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)

Body Protection

Flame retardant antistatic protective clothing.

Respiratory protection

required when vapours/aerosols are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Recommended Filter type: Filter type AX

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains. Risk of explosion.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

Appearancecolorless liquid
Odourcharacteristic
Odour Threshold0,053 ppm
pHNo data available
Melting point/freezing pointMelting point: -108,6 °C at 1.013 hPa
Initial boiling point and boiling range55 - 56 °C - lit.
Flash point-28 °C - closed cup
Evaporation rateNo data available
Flammability (solid, gas)No data available
Upper/lower flammability or explosive limitsUpper explosion limit: 8,5 %(V) Lower explosion limit: 1,6 %(V)
Vapour pressure330 hPa at 25 °C - OECD Test Guideline 104
Vapour density3.1 (vs air)
Relative density0,74 g/cm3 at 25 °C - lit. 0,74 at 20 °C
Water solubility42 g/l at 20 °C - OECD Test Guideline 105
Partition coefficient: n-octanol/waterlog Pow: 1,06 at 20 °C - OECD Test Guideline 107 - Bioaccumulation is not expected.
Autoignition temperature460 °C at 1013,0 hPa - DIN 51794 Dis
Decomposition temperatureDistillable in an undecomposed state at normal pressure.
ViscosityViscosity, kinematic: 0,409 mm2/s at 40 °C - OECD Test Guideline 1140,464 mm2/s at 20 °C - OECD Test Guideline 114 Viscosity, dynamic: 0,36 mPa.s at 20 °C
Explosive propertiesNo data available
Oxidizing propertiesNo data available
λmaxλ: 210 nm Amax: 1.0
λ: 225 nm Amax: 0.50
λ: 250 nm Amax: 0.10
λ: 300-400 nm Amax: 0.005

Other safety information

Surface tension 72,5 mN/m at 1,07g/l at 21,5 °C

- Surface tension

SECTION 10: Stability and reactivity

Reactivity

Vapors may form explosive mixture with air.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

Violent reactions possible with:

Oxidizing agents Strong acids halogens

Strong bases

Conditions to avoid

Heat, flames and sparks. Warming.

Incompatible materials

rubber, various plastics

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity

LD50 Oral - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 401)
Symptoms: Nausea, Vomiting, Pulmonary failure possible after aspiration of vomit., Aspiration may cause pulmonary edema and pneumonitis.
LC50 Inhalation - Rat - male and female - 4 h - 85 mg/l (OECD Test Guideline 403)
Symptoms: Possible damages:, mucosal irritations LD50 Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402)

Skin corrosion/irritation

Skin - Rabbit
Result: Skin irritation - 4 h (OECD Test Guideline 404)
Drying-out effect resulting in rough and chapped skin.

Serious eye damage/eye irritation

Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)

Respiratory or skin sensitization

(OECD Test Guideline 406)

Germ cell mutagenicity

No data available
Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: Mutagenicity (mammal cell test): micronucleus. Test system: mouse lymphoma cells
Metabolic activation: without metabolic activation Method: OECD Test Guideline 473
Result: negative
Test Type: unscheduled DNA synthesis assay Species: Mouse
Cell type: Liver cells
Application Route: inhalation (vapor) Method: OECD Test Guideline 486 Result: negative
Test Type: Micronucleus test Species: Mouse
Cell type: Bone marrow
Application Route: inhalation (vapor) Method: US-EPA
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration. Species: Rat
Cell type: Bone marrow
Application Route: inhalation (vapor) Method: US-EPA
Result: negative
Test Type: Transgenic rodent somatic cell gene mutation assay Species: Rat
Cell type: Bone marrow
Application Route: inhalation (vapor) Method: OECD Test Guideline 488 Result: negative

Carcinogenicity

No data available

Reproductive toxicity

No data available

Specific target organ toxicity - single exposure

No data available

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

Toxicity

. LC50 in mice (15 min): 1.6 mmol/liter of atmosphere (Marsh)

SECTION 12: Ecological information

Toxicity

Toxicity to fish

semi-static test LC50 - Menidia beryllina - 574 mg/l - 96 h (OECD Test Guideline 203)

Toxicity to daphnia and other aquatic invertebrates

flow-through test EC50 - Americamysis bahia (Mysid) - 187 mg/l - 96 h

(US-EPA OPPTS 850.1035)

Toxicity to algae

static test IC50 - Pseudokirchneriella subcapitata (green algae) - 491 mg/l - 96 h

Toxicity to bacteria

static test EC10 - Pseudomonas putida - 710 mg/l - 18 h Remarks: (ECHA)

Persistence and degradability

Biodegradability aerobic - Exposure time 28 d

Result: 0 % - Not readily biodegradable. (OECD Test Guideline 301D)

Bioaccumulative potential

Bioaccumulation Cyprinus carpio (Carp) - 28 d

at 25 °C(tert-butyl methyl ether)

Bioconcentration factor (BCF): 1,5

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

No data available

SECTION 13: Disposal considerations

Waste treatment methods

Incompatibilities

May form explosive mixture with air. Much less likely to form peroxides than other ethers. Incompatible with strong acids. Incompatible with oxidizers; contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. May accumulate static electrical charges, and cause ignition of its vapors.

Product

See www.retrologistik.com for processes regarding the return of chemicals and

containers, or contact us there if you have further questions.

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

SECTION 14: Transport information

UN number

ADR/RID: 2398 IMDG: 2398 IATA: 2398

UN proper shipping name

ADR/RID: METHYL tert-BUTYL ETHER IMDG: METHYL tert-BUTYL ETHER IATA: Methyl tert-butyl ether

Transport hazard class(es)

ADR/RID: 3 IMDG: 3 IATA: 3

Packaging group

ADR/RID: II IMDG: II IATA: II

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals

China Catalog of Hazardous chemicals 2015:Listed. website: https://www.mem.gov.cn/

Measures for Environmental Management of New Chemical Substances

Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/

United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/

Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/

New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/

Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr

European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/

EC Inventory:Listed.

Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

SECTION 16: Other information

Abbreviations and acronyms

ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
CAS: Chemical Abstracts Service
EC50: Effective Concentration 50%
IATA: International Air Transportation Association
IMDG: International Maritime Dangerous Goods
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
STEL: Short term exposure limit
TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Other Information

Much less likely to form peroxides than other ethers.

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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