Ethyl malonate (CAS 105-53-3)

Chinese name: 丙二酸二乙酯

Ethyl malonate is registered under CAS 105-53-3. Molecular formula: C7H12O4. Approximate molecular weight: 160.168. SKYSEVEN Chemical provides industrial chemical sourcing support and free CAS tools for global B2B buyers.

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Physical & identity data

CAS Number 105-53-3
English name Ethyl malonate
Chinese name 丙二酸二乙酯
Molecular formula C7H12O4
Molecular weight 160.168
Melting point -50°C
Boiling point 199?°C(lit.)
Density 5.52(vsair)
Flash point 212?°F
Refractive index n20/D1.413(lit.)
Vapor pressure 0.344mmHgat25°C
HS code (ref.) 2917190090

Applications (reference)

1、有机合成中间体。在染料、香料、磺酰脲类除草剂等生产中用途广泛。主要用于生产乙氧甲叉、巴比妥酸、烷基丙二酸二乙酯,进而合成医药如诺氟沙星、罗美沙星、氯喹、保泰松等及合成染料和颜料如苯并咪唑酮类有机颜料。还用作硝酸纤维素的增塑剂。
2、用作医药氯喹、保泰松、周效磺胺和巴比妥的中间体。
3、丙二酸酯是有机合成中十分有用的试剂,能够发生水解和脱羧反应,同时亚甲基较易形成碳负离子而发生酰化、烷基化、醛醇反应和Michael反应等。 酰化反应 丙二酸二乙酯的酰化反应会伴随有部分水解和脱羧反应,此酰化反应可应用到β

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Authority references

FAQ

What is CAS 105-53-3?

Ethyl malonate is identified by CAS Registry Number 105-53-3. Molecular formula: C7H12O4. SKYSEVEN Chemical provides industrial chemical supply and free CAS lookup tools.

Where can I buy Ethyl malonate?

Request a quote on cnchemshop.com. SKYSEVEN Chemical supplies industrial grades with COA/SDS on request for export orders.

How do I verify CAS 105-53-3 data?

Cross-check PubChem / NIST / CAS Common Chemistry, and use our free CAS lookup tool. Always match CAS on COA and invoice.

Data is for informational reference only. Verify lot-specific values with COA/SDS. Not for medical advice.