What is the difference between acid chloride and sulfonyl chloride
1. basic structure and composition
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Structure of acyl chloride An acid chloride refers to a compound in which a chlorine atom is bonded to an organic amide group, typically an amino group. Its basic structure is R-NH-Cl, wherein R represents an organic group. An acid chloride is a chloroamide commonly found in organic synthesis, especially as an activator or initiator. For example, it is often used to synthesize certain polymers or to participate in subsequent reactions as intermediates.
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Structure of sulfonyl chloride Sulfonyl chloride is a compound containing a sulfur atom, and its basic structure is R-S-Cl. Here, S is a sulfur element, and Cl is a chlorine atom. The presence of sulfur makes the properties of sulfonyl chlorides significantly different from acid chlorides, giving them a unique role in certain reactions.
And application of the difference
- Application field
- Acid chloride: commonly used in organic chemical reaction of the activator, such as in polyester synthesis or polymerization reaction of the initiator.
- Dipped acid chloride: used in some special reactions, such as thioglycoside synthesis or as a catalyst.
- Functional characteristics
- Acid chloride has a high chlorine atom activity and is easy to participate in a variety of chemical reactions, such as addition or substitution reactions.
- Dipped acid chloride due to containing sulfur elements, usually in sulfur-related reactions play a key role, such as sulfur reaction or sulfur reaction.
Photolysis Reaction Difference
of light reaction speed Under the condition of light, the reaction rate of acid chloride is usually faster, which is suitable for the reaction system requiring rapid photolysis. Due to the presence of sulfur, the photolysis rate of sulfonyl chloride may be slow, which is suitable for reactions that need to control the light environment.
Preparation methods are different
- synthetic pathway
- Acid chlorides are typically prepared by introducing a chloro reagent into the organic amide structure.
- Dip chloride is required by the introduction of sulfur elements, such as through the thiosulfate reaction, the thio group into the acyl chloride structure.
Safety and Environmental Considerations
- Toxicity and stability
- Acid chloride in different conditions of stability is higher, but in some cases may be harmful.
- Dip acid chloride because of containing sulfur, may be in the storage and use of the process of safety and environmental protection requirements are higher.
Summary
Through the above analysis, it can be seen that there are significant differences in the structure, composition, application and performance of acid chloride and sulfonyl chloride. Understanding these differences is critical for the chemical practitioner to select the right feedstock and optimize reaction conditions. In practical applications, selecting the appropriate substances according to the specific needs of the reaction can significantly improve production efficiency and product quality.
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