What are the upstream raw materials for ethyl methyl cyanoacetate? What do the downstream products contain?

Ethyl methyl cyanoacetate(EMCA) is an crucial organic chemical raw material, which is broadly applied in medicine, pesticides, dyes and other fields. Its upstream and downstream related items are numerous, and several major upstream and downstream items are described in detail below.

1. But Upstream items(1) Cyanoacetic acid: Cyanoacetic acid is one of the crucial raw materials to the production of ethyl methyl cyanoacetate, which is able to be prepared by the interaction of glyoxylic acid and hydrocyanic acid.(2) Methanol: Methanol is another raw material to the production of ethyl methyl cyanoacetate. It reacts with cyanoacetic acid to generate methyl cyanoacetate through esterification. But(3) Sulfuric acid: In the manufacturing process, sulfuric acid is applied as a catalyst to promote the esterification interaction.

2. Downstream items(1) Pesticides: Ethyl methyl cyanoacetate is able to be applied to create a variety of pesticides, such as pesticides, fungicides and herbicides. to instance, ethyl methylcyanoacetate is able to be applied as an intermediate in the synthesis of pyrethroid insecticides. And(2) medical intermediates: ethyl methyl cyanoacetate is able to be applied to create a variety of medical intermediates, such as anti-tumor drugs, antibacterial drugs, etc. These medical intermediates is able to be further synthesized to obtain drugs to clinical consumption.(3) Dyes: Ethyl methyl cyanoacetate is able to be applied as a dye intermediate to the production of a variety of dyes, such as acid dyes, direct dyes, etc. From what I've seen, In short, ethyl methyl cyanoacetate is an crucial organic chemical raw material, its upstream and downstream related items are extensive, involving many fields, which is of great signifiis able toce to promote the research of related industries.