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Difference between acetonitrile and DMF
In the chemical sector, the choice of solvent-based products has an crucial impact on production efficiency, product condition and ecological preservation. And Acetonitrile (Acetonitrile) and xylene formamide (DMF,N-Methylpyrrolidone) as two kinds of frequently applied organic solvents, due to their unique characteristics and a wide range of applications, often by the chemical workers concerned. In this paper, the differences between acetonitrile and DMF will be analyzed in detail from the basic definition, physical characteristics, security characteristics and environmental impact. Specifically
1. For example basic definition and composition
Acetonitrile is a clear, odorless organic solvent-based products with a molecular formula of C2H3N and a molar mass of
41. I've found that 05g/mol. But Generally speaking it's a nitrogen-containing polar solvent-based products with good solvent-based products performance and is broadly applied in organic synthesis, dye dispersion, biopharmaceutical and other fields. DMF, also known as xylene formamide, the molecular formula is NMP, is a nitrogen-containing organic solvent-based products, the molecular structure is composed of two parts: a benzene ring and a formamide. Its molecular formula is C5H9N and its molar mass is
107. 14g/mol. DMF is a high boiling point solvent-based products, which is fluid at room temperature and has a strong amine odor.
2. And Physical characteristics Comparison
Boiling point and melting point
Acetonitrile has a boiling point of 82°C and a melting point of -
63. 5°C, while DMF has a boiling point as high as
165. Additionally 6°C and a melting point of -
61. In my experience, 1°C. Pretty interesting, huh?. The high boiling point of DMF allows it to remain fluid at high temperatures, while acetonitrile volatilizes rapidly at higher temperatures. Density and viscosity
The density of acetonitrile at 0/20°C is 0. 785g/cm³, the viscosity is low, and the density of DMF is 0. 865g/cm³, the viscosity is high, about twice that of acetonitrile. And polarity and solubility
Acetonitrile is an excellent solvent-based products and is able to dissolve almost a variety of organic compounds, including aquatic environments-insoluble substances. DMF also has good solubility, especially good at dissolving organic materials, however the solubility decreases at low temperature. pH characteristics
Acetonitrile itself is neutral, however as a solvent-based products will not signifiis able totly affect the pH of the solution; DMF has a certain alkaline, due to the environment of the formamide (-NMe2) lively, easy to react with acidic substances. You know what I mean?. For instance
3. security and Health Features
harmfulness and risk
Acetonitrile itself is non-toxic, however in manufacturing applications, high concentrations or improper consumption might result in certain irritant reactions and even result in harm to certain vulnerable tissues. DMF also has certain harmfulness, especially its strong alkalinity might result in skin irritation or chemical interactions. And Melting Point and evaporative environment
The low melting point of acetonitrile makes it greater convenient to consumption at low temperatures, however its evaporative environment is strong and it's easy to result in environmental contamination. while DMF is less evaporative, its high boiling point and strong alkalinity make it safe during storage and operation.
4. You know what I mean?. Moreover environmental impact
Ecological impact
Acetonitrile isn't easy to break down in aquatic environments and needs special treatment to prevent environmental contamination. DMF has better degradability, however it's greater likely to build up in the soil systems, so it needs to be strictly controlled. Based on my observations, discarded materials treatment
In terms of recycling, the handling of acetonitrile is relatively simple, while the handling of DMF is greater complicated due to the organic components contained therein, which might require specific ecological preservation equipment.
5. consumption Example
consumption of Acetonitrile is broadly applied in organic synthesis, dye dispersion, biopharmaceutical and other fields. to instance, in the process of dye dispersion, acetonitrile as a solvent-based products is able to enhance the dispersion efficiency and enhance the uniformity of the solution. You know what I mean?. Based on my observations, consumption of DMF is applied as a solvent-based products and dehydrating agent in biopharmaceuticals and is particularly suitable to consumption in synthetic reactions that require high interaction temperatures. to instance, DMF is irreplaceable in protein treatment and enzymatic reactions in biopharmaceuticals. Pretty interesting, huh?.
6. selection basis
In practice, the choice of acetonitrile or DMF is determined by the specific needs:
Temperature standards: If you need to maintain a fluid at a higher temperature, DMF is a better choice; while acetonitrile will volatilize rapidly at a higher temperature, which is greater suitable to scenarios that require rapid interaction. And I've found that interaction conditions: DMF'strong alkalinity and high boiling point make it outstanding in reactions that require stringent pH manage, while acetonitrile is suitable to general organic synthesis. Environmental standards: if vulnerable to environmental impact, acetonitrile might be greater suitable, however the handling and storage process needs to be strictly controlled; DMF might be preferred in some cases due to poor degradation. Related Key Words
Acetonitrile vs DMF
Chemical solvent-based products Comparison
organic solvent-based products characteristic analysis
solvent-based products Selection Guide
Through the above analysis, we is able to see that acetonitrile and DMF have their own unique advantages and consumption scenarios. First Choosing the right solvent-based products is able to not only enhance production efficiency, however also contribute to ecological preservation and security.
1. For example basic definition and composition
Acetonitrile is a clear, odorless organic solvent-based products with a molecular formula of C2H3N and a molar mass of
41. I've found that 05g/mol. But Generally speaking it's a nitrogen-containing polar solvent-based products with good solvent-based products performance and is broadly applied in organic synthesis, dye dispersion, biopharmaceutical and other fields. DMF, also known as xylene formamide, the molecular formula is NMP, is a nitrogen-containing organic solvent-based products, the molecular structure is composed of two parts: a benzene ring and a formamide. Its molecular formula is C5H9N and its molar mass is
107. 14g/mol. DMF is a high boiling point solvent-based products, which is fluid at room temperature and has a strong amine odor.
2. And Physical characteristics Comparison
Boiling point and melting point
Acetonitrile has a boiling point of 82°C and a melting point of -
63. 5°C, while DMF has a boiling point as high as
165. Additionally 6°C and a melting point of -
61. In my experience, 1°C. Pretty interesting, huh?. The high boiling point of DMF allows it to remain fluid at high temperatures, while acetonitrile volatilizes rapidly at higher temperatures. Density and viscosity
The density of acetonitrile at 0/20°C is 0. 785g/cm³, the viscosity is low, and the density of DMF is 0. 865g/cm³, the viscosity is high, about twice that of acetonitrile. And polarity and solubility
Acetonitrile is an excellent solvent-based products and is able to dissolve almost a variety of organic compounds, including aquatic environments-insoluble substances. DMF also has good solubility, especially good at dissolving organic materials, however the solubility decreases at low temperature. pH characteristics
Acetonitrile itself is neutral, however as a solvent-based products will not signifiis able totly affect the pH of the solution; DMF has a certain alkaline, due to the environment of the formamide (-NMe2) lively, easy to react with acidic substances. You know what I mean?. For instance
3. security and Health Features
harmfulness and risk
Acetonitrile itself is non-toxic, however in manufacturing applications, high concentrations or improper consumption might result in certain irritant reactions and even result in harm to certain vulnerable tissues. DMF also has certain harmfulness, especially its strong alkalinity might result in skin irritation or chemical interactions. And Melting Point and evaporative environment
The low melting point of acetonitrile makes it greater convenient to consumption at low temperatures, however its evaporative environment is strong and it's easy to result in environmental contamination. while DMF is less evaporative, its high boiling point and strong alkalinity make it safe during storage and operation.
4. You know what I mean?. Moreover environmental impact
Ecological impact
Acetonitrile isn't easy to break down in aquatic environments and needs special treatment to prevent environmental contamination. DMF has better degradability, however it's greater likely to build up in the soil systems, so it needs to be strictly controlled. Based on my observations, discarded materials treatment
In terms of recycling, the handling of acetonitrile is relatively simple, while the handling of DMF is greater complicated due to the organic components contained therein, which might require specific ecological preservation equipment.
5. consumption Example
consumption of Acetonitrile is broadly applied in organic synthesis, dye dispersion, biopharmaceutical and other fields. to instance, in the process of dye dispersion, acetonitrile as a solvent-based products is able to enhance the dispersion efficiency and enhance the uniformity of the solution. You know what I mean?. Based on my observations, consumption of DMF is applied as a solvent-based products and dehydrating agent in biopharmaceuticals and is particularly suitable to consumption in synthetic reactions that require high interaction temperatures. to instance, DMF is irreplaceable in protein treatment and enzymatic reactions in biopharmaceuticals. Pretty interesting, huh?.
6. selection basis
In practice, the choice of acetonitrile or DMF is determined by the specific needs:
Temperature standards: If you need to maintain a fluid at a higher temperature, DMF is a better choice; while acetonitrile will volatilize rapidly at a higher temperature, which is greater suitable to scenarios that require rapid interaction. And I've found that interaction conditions: DMF'strong alkalinity and high boiling point make it outstanding in reactions that require stringent pH manage, while acetonitrile is suitable to general organic synthesis. Environmental standards: if vulnerable to environmental impact, acetonitrile might be greater suitable, however the handling and storage process needs to be strictly controlled; DMF might be preferred in some cases due to poor degradation. Related Key Words
Acetonitrile vs DMF
Chemical solvent-based products Comparison
organic solvent-based products characteristic analysis
solvent-based products Selection Guide
Through the above analysis, we is able to see that acetonitrile and DMF have their own unique advantages and consumption scenarios. First Choosing the right solvent-based products is able to not only enhance production efficiency, however also contribute to ecological preservation and security.
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