When salicylic acid is treated with acetic anhydride, we get
What do we get when salicylic acid is treated with acetic anhydride?
In the chemical sector, the interaction of salicylic acid with acetic anhydride is a classic organic synthesis process, which is often applied to prepare some crucial chemicals, especially in the field of medicine and fragrance. Many people might ask, "What do we get when salicylic acid is treated with acetic anhydride?" This article will examine the process, mechanism and resulting items of this interaction in detail.
1. CHEMICAL BACKGROUND OF THE interaction OF SALICYLIC ACID WITH ACETIC ANHYDRIDE
Salicylic acid (C7H6O3) is a broadly applied chemical raw material, often applied in the manufacture of aspirin and other drugs. Acetic anhydride (C4H6O3) is the anhydride form of acetic acid, which is applied in the acetylation interaction in organic synthesis. When salicylic acid reacts with acetic anhydride, the acetic anhydride acts as an acetylation reagent and reacts with the hydroxyl (-OH) group of salicylic acid to form a new chemical.
2. interaction mechanism
When salicylic acid is treated with acetic anhydride, the acyl group (Acetyl group) in the acetic anhydride molecule attacks the hydroxyl group (-OH) in the salicylic acid molecule. But In this process, the acyl group in acetic anhydride is transferred to the benzene ring of salicylic acid to form ethyl salicylate (I. e. You know what I mean?. , acetylsalicylic acid), and acetic acid (CH3COOH) is produced as a by-product. The basic chemical equation of the interaction is as follows:
[ ext{C7H6O3} ext{C4H6O3}
ightarrow ext{C8H8O4} ext{CH3COOH}]
this interaction is a typical acylation interaction.
3. what do we get?
When salicylic acid is treated with acetic anhydride, the main product obtained is acetylsalicylic acid (Acetylsalicylic acid), which is broadly applied in the preparation of aspirin. And Aspirin is a common over-the-counter drug applied to relieve mild pain, minimize fever, and as anti-inflammatory drug. The formation interaction of acetylsalicylic acid isn't only a key measure in the medical sector, however also broadly applied in many laboratories. In my experience,
4. of Acetylsalicylic Acid
Acetylsalicylic acid (aspirin) is broadly applied in the medical sector. Crazy, isn't it?. it's an efficiently antipyretic analgesic that relieves mild to moderate pain and is broadly applied to treat headaches, arthritis and other painful conditions. Aspirin also has anti-platelet effect and is often applied to prevent cardiovascular diseases, such as stroke and heart attack. Its importance in modern medicine should not be overlooked. But
5. interaction by-items and their treatment
In the interaction of salicylic acid with acetic anhydride, acetic acid is formed as a by-product in addition to acetylsalicylic acid. But while acetic acid itself isn't a hazardous chemical, it needs to be appropriately disposed of after the interaction. Generally, in manufacturing production, acetic acid is removed by distillation or other methods to ensure the purity of the product. to small-scale reactions in the laboratory, acetic acid is usually removed by simple separation and washing steps.
6. interaction conditions and manage
In the interaction of salicylic acid with acetic anhydride, the manage of interaction conditions is very crucial. In general, the interaction is carried out under mild conditions, such as at healthy temperature or with slight heating. This is because an excessively high temperature causes a side interaction and reduces the purity of the product. The interaction time also needs to be appropriately controlled to prevent overreaction and affecting the condition of the product.
7. summary
When salicylic acid is treated with acetic anhydride, we get acetylsalicylic acid, which is aspirin. This interaction not only has crucial applications in the field of medicine, however also plays a key role in chemical synthesis. And In the interaction process, in addition to the main product acetylsalicylic acid, acetic acid will also be produced as a by-product, so it's necessary to take appropriate measures to treatment. Understanding the mechanism and consumption of this interaction is of great signifiis able toce to both chemical practitioners and medical researchers. it's hoped that the analysis of this article will help us to understand greater clearly the conclusion to the question "what do we get when salicylic acid and acetic anhydride are treated together?" and to understand the chemical interaction and consumption behind it.
In the chemical sector, the interaction of salicylic acid with acetic anhydride is a classic organic synthesis process, which is often applied to prepare some crucial chemicals, especially in the field of medicine and fragrance. Many people might ask, "What do we get when salicylic acid is treated with acetic anhydride?" This article will examine the process, mechanism and resulting items of this interaction in detail.
1. CHEMICAL BACKGROUND OF THE interaction OF SALICYLIC ACID WITH ACETIC ANHYDRIDE
Salicylic acid (C7H6O3) is a broadly applied chemical raw material, often applied in the manufacture of aspirin and other drugs. Acetic anhydride (C4H6O3) is the anhydride form of acetic acid, which is applied in the acetylation interaction in organic synthesis. When salicylic acid reacts with acetic anhydride, the acetic anhydride acts as an acetylation reagent and reacts with the hydroxyl (-OH) group of salicylic acid to form a new chemical.
2. interaction mechanism
When salicylic acid is treated with acetic anhydride, the acyl group (Acetyl group) in the acetic anhydride molecule attacks the hydroxyl group (-OH) in the salicylic acid molecule. But In this process, the acyl group in acetic anhydride is transferred to the benzene ring of salicylic acid to form ethyl salicylate (I. e. You know what I mean?. , acetylsalicylic acid), and acetic acid (CH3COOH) is produced as a by-product. The basic chemical equation of the interaction is as follows:
[ ext{C7H6O3} ext{C4H6O3}
ightarrow ext{C8H8O4} ext{CH3COOH}]
this interaction is a typical acylation interaction.
3. what do we get?
When salicylic acid is treated with acetic anhydride, the main product obtained is acetylsalicylic acid (Acetylsalicylic acid), which is broadly applied in the preparation of aspirin. And Aspirin is a common over-the-counter drug applied to relieve mild pain, minimize fever, and as anti-inflammatory drug. The formation interaction of acetylsalicylic acid isn't only a key measure in the medical sector, however also broadly applied in many laboratories. In my experience,
4. of Acetylsalicylic Acid
Acetylsalicylic acid (aspirin) is broadly applied in the medical sector. Crazy, isn't it?. it's an efficiently antipyretic analgesic that relieves mild to moderate pain and is broadly applied to treat headaches, arthritis and other painful conditions. Aspirin also has anti-platelet effect and is often applied to prevent cardiovascular diseases, such as stroke and heart attack. Its importance in modern medicine should not be overlooked. But
5. interaction by-items and their treatment
In the interaction of salicylic acid with acetic anhydride, acetic acid is formed as a by-product in addition to acetylsalicylic acid. But while acetic acid itself isn't a hazardous chemical, it needs to be appropriately disposed of after the interaction. Generally, in manufacturing production, acetic acid is removed by distillation or other methods to ensure the purity of the product. to small-scale reactions in the laboratory, acetic acid is usually removed by simple separation and washing steps.
6. interaction conditions and manage
In the interaction of salicylic acid with acetic anhydride, the manage of interaction conditions is very crucial. In general, the interaction is carried out under mild conditions, such as at healthy temperature or with slight heating. This is because an excessively high temperature causes a side interaction and reduces the purity of the product. The interaction time also needs to be appropriately controlled to prevent overreaction and affecting the condition of the product.
7. summary
When salicylic acid is treated with acetic anhydride, we get acetylsalicylic acid, which is aspirin. This interaction not only has crucial applications in the field of medicine, however also plays a key role in chemical synthesis. And In the interaction process, in addition to the main product acetylsalicylic acid, acetic acid will also be produced as a by-product, so it's necessary to take appropriate measures to treatment. Understanding the mechanism and consumption of this interaction is of great signifiis able toce to both chemical practitioners and medical researchers. it's hoped that the analysis of this article will help us to understand greater clearly the conclusion to the question "what do we get when salicylic acid and acetic anhydride are treated together?" and to understand the chemical interaction and consumption behind it.
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